PUBLICATION
Increased diameter of arteries and veins in the caudal fins of Danio reriolongfin t2 fish is accompanied by fin overgrowth
- Authors
- Lanni, J.S., Lyon, B.W., Nguyen, S.V.
- ID
- ZDB-PUB-260224-3
- Date
- 2026
- Source
- microPublication. Biology 2026: (Journal)
- Registered Authors
- Keywords
- none
- MeSH Terms
- none
- PubMed
- 41728344 Full text @ MicroPubl Biol
Citation
Lanni, J.S., Lyon, B.W., Nguyen, S.V. (2026) Increased diameter of arteries and veins in the caudal fins of Danio reriolongfin t2 fish is accompanied by fin overgrowth. microPublication. Biology. 2026:.
Abstract
The classic dominant longfin zebrafish strain ( lof t2 ) has long fins due to ectopic expression of the potassium channel Kcnh2a in the fin mesenchyme. Potassium channel function is also known to affect the vasculature, but the fin vasculature has not been characterized in lof t2 fish. Here we show that lof t2 fish contain significantly increased artery and vein diameters in the caudal fin as compared to wildtype fish. Interestingly, these changes in blood vessel size are associated with areas of fin overgrowth, consistent with a possible role for the vasculature in fin size regulation. .
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping