PUBLICATION
Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism
- Authors
- Hogan, A.L., Kane, M., Chiu, P., Richter, G., Maurel, C., Wu, S., Scherer, N.M., Don, E.K., Lee, A., Blair, I.P., Chung, R.S., Morsch, M.
- ID
- ZDB-PUB-251203-8
- Date
- 2025
- Source
- Acta neuropathologica communications 14: 63 (Journal)
- Registered Authors
- Chung, Roger, Don, Emily, Morsch, Marco
- Keywords
- Alzheimer’s disease, Amyotrophic lateral sclerosis, Frontotemporal lobar dementia, Motor neurons, Neurodegeneration, TDP-43, Zebrafish
- MeSH Terms
- none
- PubMed
- 41331940 Full text @ Acta Neuropathol Commun
Citation
Hogan, A.L., Kane, M., Chiu, P., Richter, G., Maurel, C., Wu, S., Scherer, N.M., Don, E.K., Lee, A., Blair, I.P., Chung, R.S., Morsch, M. (2025) Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism. Acta neuropathologica communications. 14:63.
Abstract
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping