PUBLICATION
Bioconversion of agriculture by-products with functionally enhanced Streptomyces sp. SCUT-3: Fish skin as a model
- Authors
- Ni, J.T., Zhang, M.S., Lu, D.L., Lu, W.J., Wu, L., Yang, Z.D., Qin, C., Dai, Z.J., Li, Z.W., Feng, W.J., Cai, H.H., Zhang, J.R., Liang, C.Y., Deng, J.J., Luo, X.C.
- ID
- ZDB-PUB-240908-3
- Date
- 2024
- Source
- Food Chemistry 463: 141106141106 (Journal)
- Registered Authors
- Luo, Xiaochun
- Keywords
- Anti-aging, Anti-inflammation, Bioconversion, Collagen hydrolysates, Oligopeptide
- MeSH Terms
-
- Animals
- Collagen/chemistry
- Collagen/metabolism
- Fermentation
- Fibroblasts/metabolism
- Humans
- Skin*/metabolism
- Streptomyces*/chemistry
- Streptomyces*/metabolism
- Tilapia/metabolism
- Zebrafish*/metabolism
- PubMed
- 39241423 Full text @ Food Chem.
Citation
Ni, J.T., Zhang, M.S., Lu, D.L., Lu, W.J., Wu, L., Yang, Z.D., Qin, C., Dai, Z.J., Li, Z.W., Feng, W.J., Cai, H.H., Zhang, J.R., Liang, C.Y., Deng, J.J., Luo, X.C. (2024) Bioconversion of agriculture by-products with functionally enhanced Streptomyces sp. SCUT-3: Fish skin as a model. Food Chemistry. 463:141106141106.
Abstract
With the global population continuously rising, efficient bioconversion of inedible agricultural by-products is crucial for human food and energy sustainability. We here propose solid-state fermentation approaches to efficiently convert biopolymers into oligomers/monomers by accelerating the natural degradation process of the versatile Streptomyces sp. strain SCUT-3. Using fish skin as a representative by-product, 54.3 g amino acids and 14.7 g peptides (91 % < 2500 Da) were recovered from 89.0 g protein in 100 g tilapia skin sample by collagenase-overexpressed SCUT-3 for seven days at a 1:4 substrate:liquid ratio. Fish skin collagen hydrolysates exhibited excellent anti-oxidation, anti-hypertension, scratch-repairing, anti-aging, anti-ultraviolet radiation, and anti-inflammation effects on human skin fibroblasts In vitro and zebrafish larvae in vivo, indicating their potential applications in healthcare/skincare and anti-atopic dermatitis. As Laozi said, the divine law follows nature. This study underscores the efficacy of genetically engineered SCUT-3 according to its natural biomass utilization laws in large-scale biopolymer conversion.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping