PUBLICATION
Zebrafish models for pathogenic Vibrios
- Authors
- Nag, D., Farr, D., Walton, M.G., Withey, J.H.
- ID
- ZDB-PUB-200812-3
- Date
- 2020
- Source
- Journal of bacteriology 202(24): (Review)
- Registered Authors
- Keywords
- none
- MeSH Terms
-
- Disease Models, Animal*
- Humans
- Vibrio/classification
- Vibrio/genetics
- Vibrio/pathogenicity
- Vibrio/physiology*
- Zebrafish*/microbiology
- Animals
- Vibrio Infections/microbiology*
- Virulence
- PubMed
- 32778562 Full text @ J. Bacteriol.
Citation
Nag, D., Farr, D., Walton, M.G., Withey, J.H. (2020) Zebrafish models for pathogenic Vibrios. Journal of bacteriology. 202(24):.
Abstract
Vibrio is a large and diverse genus of bacteria, most of which are non-pathogenic species found in the aquatic environment. However, a subset of the Vibrio genus includes several species that are highly pathogenic, either to humans or to aquatic animals. In recent years, Danio rerio, commonly known as the zebrafish, has emerged as a major animal model used for studying nearly every aspect of biology, including infectious diseases. Zebrafish are especially useful because the embryos are transparent, larvae are small and facilitate imaging studies, and numerous transgenic fish strains have been constructed. Zebrafish models for several pathogenic Vibrio species have been described, and indeed a fish model is highly relevant for the study of aquatic bacterial pathogens. Here, we summarize the zebrafish models that have been used to study pathogenic Vibrio species to date.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping