PUBLICATION

Freezing activity brief data from a new FUS mutant zebrafish line

Authors
Campanari, M.L., Bourefis, A.R., Buee-Scherrer, V., Kabashi, E.
ID
ZDB-PUB-200719-5
Date
2020
Source
Data in brief   31: 105921 (Journal)
Registered Authors
Keywords
Behaviour, FUS KO model, Freezing response, Visual stimulation with the automatized viewpoint zebrabox system, Zebrafish (Danio Rerio)
MeSH Terms
none
PubMed
32676526 Full text @ Data Brief
Abstract
The data presented in this paper are related to the research article "Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS". In this model the lack of fus causes reduced lifespan as well as impaired motor abilities associated with a decrease of motor neurons axons lenght and an increase of neuromuscular junctions fragmentation. Data in this article describes the global locomotor activity data at 3, 4 and 5 days post fertilization in WT, fus heterozygous (fus+/-) and fus homozygous (fus-/-) zebrafish embryos as a response to visual light stimulation, with particular attention on the freezing respose.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping