PUBLICATION
Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5)
- Authors
- Cudia, D., Ames, J.B.
- ID
- ZDB-PUB-190203-1
- Date
- 2019
- Source
- Biomolecular NMR assignments 13(1): 201-205 (Journal)
- Registered Authors
- Keywords
- EF-hand, GCAP5, Phototransduction, RetGC, Retinal guanylyl cyclase
- MeSH Terms
-
- Zebrafish/metabolism*
- Animals
- Retina/metabolism*
- Protein Structure, Secondary
- Amino Acid Sequence
- Nuclear Magnetic Resonance, Biomolecular*
- Zebrafish Proteins/chemistry*
- Guanylate Cyclase-Activating Proteins/chemistry*
- PubMed
- 30706384 Full text @ Biomol. NMR Assign.
Citation
Cudia, D., Ames, J.B. (2019) Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5). Biomolecular NMR assignments. 13(1):201-205.
Abstract
Retinal membrane guanylyl cyclase (RetGC) in photoreceptor rod and cone cells is regulated by a family of guanylyl cyclase activating proteins (GCAP1-7). GCAP5 is expressed in zebrafish photoreceptors and promotes Ca2+-dependent regulation of RetGC enzymatic activity that regulates visual phototransduction. We report NMR chemical shift assignments of the Ca2+-free activator form of GCAP5 (BMRB No. 27705).
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping