PUBLICATION
The effects of dietary supplement of galactooligosaccharide on innate immunity, immune related genes expression and growth performance in zebrafish (Danio rerio)
- Authors
- Yousefi, S., Hoseinifar, S.H., Paknejad, H., Hajimoradloo, A.
- ID
- ZDB-PUB-171221-2
- Date
- 2017
- Source
- Fish & shellfish immunology 73: 192-196 (Journal)
- Registered Authors
- Keywords
- Galactooligosaccharide, Gene expression, Growth performance, Innate immunity, Zebrafish
- MeSH Terms
-
- Animal Feed/analysis
- Immunity, Innate/genetics*
- Gene Expression Regulation/immunology*
- Dietary Supplements/analysis
- Oligosaccharides/administration & dosage
- Oligosaccharides/metabolism*
- Diet/veterinary
- Animals
- Zebrafish/genetics*
- Zebrafish/growth & development
- Zebrafish/immunology*
- PubMed
- 29258754 Full text @ Fish Shellfish Immunol.
Citation
Yousefi, S., Hoseinifar, S.H., Paknejad, H., Hajimoradloo, A. (2017) The effects of dietary supplement of galactooligosaccharide on innate immunity, immune related genes expression and growth performance in zebrafish (Danio rerio). Fish & shellfish immunology. 73:192-196.
Abstract
The present study investigates the effect of different levels of galactooligosaccharide (GOS) on innate immune parameters, immune related genes expression as well as growth performance in zebrafish (Danio rerio). Four hundred and twenty fish (mean weight 45?±?0.1?mg) were supplied, randomly stocked in twelve aquaria assigned to four treatments. Zebrafish were fed with either control diet or control diet enriched with different levels (0.5, 1 and 2%) of GOS for eight weeks. At the end of feeding trial innate immune parameters (total immunoglobulin, total protein and alkaline phosphatase activity), immune related genes expression (interleukin 1 beta [il1b], Lysozyme [lyz], tumor necrosis factor alpha [tnf-alpha]) as well as growth performance were measured. Evaluation of immune parameters revealed significant (P??.05) differences were noticed between GOS fed fish and control group. Also, in case of ALP activity, significant increase (P??.05) difference was observed in case of il1b gene expression. Evaluation of growth performance at the end of feeding trial revealed no significant (P?
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping