PUBLICATION
Voltage-sensing phosphatase: actions and potentials
- Authors
- Okamura, Y., Murata, Y., Iwasaki, H.
- ID
- ZDB-PUB-171023-2
- Date
- 2009
- Source
- The Journal of physiology 587(3): 513-20 (Review)
- Registered Authors
- Keywords
- none
- MeSH Terms
-
- Neurons/enzymology
- Neurons/physiology*
- Phosphotransferases (Alcohol Group Acceptor)/metabolism
- Ion Channels/chemistry
- Ion Channels/metabolism
- PubMed
- 19074969 Full text @ J. Physiol.
Abstract
Voltage sensors have been well studied in voltage-gated ion channels for neuronal excitation and muscle contraction. The recent discovery of a voltage-sensing phosphatase, VSP, has changed the idea that voltage sensors are unique to ion flux through membranes. Recent findings on mechanisms and potential applications of VSP are reviewed.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping