PUBLICATION

Regeneration Tensed Up: Polyploidy Takes the Lead

Authors
Spiró, Z., Heisenberg, C.P.
ID
ZDB-PUB-170928-9
Date
2017
Source
Developmental Cell   42: 559-560 (Review)
Registered Authors
Heisenberg, Carl-Philipp
Keywords
none
MeSH Terms
  • Animals
  • Heart
  • Polyploidy
  • Regeneration*
  • Zebrafish*
  • Zebrafish Proteins/genetics
PubMed
28950096 Full text @ Dev. Cell
Citation
Spiró, Z., Heisenberg, C.P. (2017) Regeneration Tensed Up: Polyploidy Takes the Lead. Developmental Cell. 42:559-560.
Abstract
The cellular mechanisms allowing tissues to efficiently regenerate are not fully understood. In this issue of Developmental Cell, Cao et al. (2017) discover that during zebrafish heart regeneration, epicardial cells at the leading edge of regenerating tissue undergo endoreplication, possibly due to increased tissue tension, thereby boosting their regenerative capacity.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
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