PUBLICATION
Behavioural effect of low-dose BPA on male zebrafish: Tuning of male mating competition and female mating preference during courtship process
- Authors
- Li, X., Guo, J.Y., Li, X., Zhou, H.J., Zhang, S.H., Liu, X.D., Chen, D.Y., Fang, Y.C., Feng, X.Z.
- ID
- ZDB-PUB-161118-1
- Date
- 2017
- Source
- Chemosphere 169: 40-52 (Journal)
- Registered Authors
- Li, Xiang
- Keywords
- Behavior, Courtship, Low-dose bisphenol A, Zebrafish
- MeSH Terms
-
- Animals
- Behavior, Animal/drug effects*
- Benzhydryl Compounds/toxicity*
- Courtship/psychology*
- Endocrine Disruptors/toxicity*
- Environmental Pollution
- Female
- Male
- Phenols/toxicity*
- Social Behavior
- Toxicity Tests
- Water Pollutants, Chemical/toxicity*
- Zebrafish/physiology*
- PubMed
- 27855330 Full text @ Chemosphere
- CTD
- 27855330
Citation
Li, X., Guo, J.Y., Li, X., Zhou, H.J., Zhang, S.H., Liu, X.D., Chen, D.Y., Fang, Y.C., Feng, X.Z. (2017) Behavioural effect of low-dose BPA on male zebrafish: Tuning of male mating competition and female mating preference during courtship process. Chemosphere. 169:40-52.
Abstract
The ubiquity of environmental pollution by endocrine disrupting chemicals (EDCs) such as bisphenol A (BPA) is progressively considered as a major threat to aquatic ecosystems worldwide. Numerous toxicological studies have proved that BPA are hazardous to aquatic environment, along with alterations in the development and physiology of aquatic vertebrates. However, generally, there is a paucity in knowledge of behavioural and physiological effects of BPA with low concentration, for example, 0.22 nM (50 ng/L) and 2.2 nM (500 ng/L). Here we show that treatment of adult male zebrafish (Danio rerio) with 7 weeks low-dose (0.22 nM-2.2 nM) BPA, resulted in alteration in histological structure of testis tissue and abnormality in expression levels of genes involved in testicular steroidogenesis. Furthermore, low-dose BPA treatment decreased the male locomotion during courtship; and was associated with less courtship behaviours to female but more aggressive behaviours to mating competitor. Interestingly, during the courtship test, we observed that female preferred control male to male under low-dose BPA exposure. Subsequently, we found that the ability of female to chose optimal mating male through socially mutual interaction and dynamics of male zebrafish, which was based on visual discrimination. In sum, our results shed light on the potential behavioural and physiological effect of low-dose BPA exposure on courtship behaviours of zebrafish, which could exert profound consequences on natural zebrafish populations.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping