PUBLICATION
Mixtures, Metabolites, and Mechanisms: Understanding Toxicology Using Zebrafish
- Authors
- Gamse, J.T., Gorelick, D.A.
- ID
- ZDB-PUB-160913-3
- Date
- 2016
- Source
- Zebrafish 13: 377-378 (Review)
- Registered Authors
- Gamse, Josh, Gorelick, Daniel
- Keywords
- none
- MeSH Terms
-
- Animals
- Models, Animal
- Toxicology*
- Zebrafish/embryology
- Zebrafish/metabolism*
- Water Pollutants, Chemical/toxicity*
- PubMed
- 27618129 Full text @ Zebrafish
Citation
Gamse, J.T., Gorelick, D.A. (2016) Mixtures, Metabolites, and Mechanisms: Understanding Toxicology Using Zebrafish. Zebrafish. 13:377-378.
Abstract
For more than 60 years, zebrafish have been used in toxicological studies. Due to their transparency, genetic tractability, and compatibility with high-throughput screens, zebrafish embryos are uniquely suited to study the effects of pharmaceuticals and environmental insults on embryonic development, organ formation and function, and reproductive success. This special issue of Zebrafish highlights the ways zebrafish are used to investigate the toxic effects of endocrine disruptors, pesticides, and heavy metals.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping