PUBLICATION
Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals
- Authors
- Kim, J.W., Yang, H.J., Oel, A.P., Brooks, M.J., Jia, L., Plachetzki, D.C., Li, W., Allison, W.T., Swaroop, A.
- ID
- ZDB-PUB-160622-5
- Date
- 2016
- Source
- Developmental Cell 37: 520-532 (Journal)
- Registered Authors
- Allison, Ted, Jia, Li, Li, Wei, Oel, Phil
- Keywords
- none
- MeSH Terms
-
- Animals
- Basic-Leucine Zipper Transcription Factors/metabolism
- Biological Evolution*
- Cell Lineage/genetics
- Cell Lineage/radiation effects
- Chickens
- Chromatin/metabolism
- Epigenesis, Genetic/radiation effects
- Eye Proteins/metabolism
- Gene Expression Regulation, Developmental/radiation effects
- Light*
- Mammals/genetics
- Mammals/metabolism*
- Mice
- Night Vision/radiation effects*
- Opsins/metabolism
- Regulatory Sequences, Nucleic Acid/genetics
- Retinal Cone Photoreceptor Cells/metabolism*
- Retinal Cone Photoreceptor Cells/radiation effects
- Retinal Rod Photoreceptor Cells/metabolism*
- Retinal Rod Photoreceptor Cells/radiation effects
- Ultraviolet Rays
- Zebrafish/embryology
- Zebrafish/metabolism
- PubMed
- 27326930 Full text @ Dev. Cell
Citation
Kim, J.W., Yang, H.J., Oel, A.P., Brooks, M.J., Jia, L., Plachetzki, D.C., Li, W., Allison, W.T., Swaroop, A. (2016) Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals. Developmental Cell. 37:520-532.
Abstract
Vertebrate ancestors had only cone-like photoreceptors. The duplex retina evolved in jawless vertebrates with the advent of highly photosensitive rod-like photoreceptors. Despite cones being the arbiters of high-resolution color vision, rods emerged as the dominant photoreceptor in mammals during a nocturnal phase early in their evolution. We investigated the evolutionary and developmental origins of rods in two divergent vertebrate retinas. In mice, we discovered genetic and epigenetic vestiges of short-wavelength cones in developing rods, and cell-lineage tracing validated the genesis of rods from S cones. Curiously, rods did not derive from S cones in zebrafish. Our study illuminates several questions regarding the evolution of duplex retina and supports the hypothesis that, in mammals, the S-cone lineage was recruited via the Maf-family transcription factor NRL to augment rod photoreceptors. We propose that this developmental mechanism allowed the adaptive exploitation of scotopic niches during the nocturnal bottleneck early in mammalian evolution.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping