PUBLICATION
Zebrafish kidney development
- Authors
- Drummond, I.A., Davidson, A.J.
- ID
- ZDB-PUB-160618-11
- Date
- 2016
- Source
- Methods in cell biology 134: 391-429 (Chapter)
- Registered Authors
- Davidson, Alan, Drummond, Iain
- Keywords
- Kidney, Nephron, Organogenesis, Pronephros, Regeneration
- MeSH Terms
-
- Animals
- Gene Expression Regulation, Developmental
- Humans
- Kidney/growth & development*
- Nephrons/growth & development
- Organogenesis/genetics*
- Pronephros/growth & development
- Regeneration/genetics*
- Zebrafish/genetics
- Zebrafish/growth & development
- PubMed
- 27312500 Full text @ Meth. Cell. Biol.
Citation
Drummond, I.A., Davidson, A.J. (2016) Zebrafish kidney development. Methods in cell biology. 134:391-429.
Abstract
The kidney of the zebrafish shares many features with other vertebrate kidneys including the human kidney. Similar cell types and shared developmental and patterning mechanisms make the zebrafish pronephros a valuable model for kidney organogenesis. Here we review recent advances in studies of zebrafish pronephric development and provide experimental protocols to analyze kidney cell types and structures, measure nephron function, live image kidney cells in vivo, and probe mechanisms of kidney regeneration after injury.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping