PUBLICATION
The Cellular Organization of Zebrafish Visuomotor Circuits
- Authors
- Orger, M.B.
- ID
- ZDB-PUB-160512-5
- Date
- 2016
- Source
- Current biology : CB 26: R377-R385 (Review)
- Registered Authors
- Orger, Mike
- Keywords
- none
- MeSH Terms
-
- Animals
- Brain/cytology*
- Brain/physiology*
- Brain Mapping*
- Nerve Net/physiology*
- Neurons/physiology*
- Zebrafish*
- PubMed
- 27166700 Full text @ Curr. Biol.
Citation
Orger, M.B. (2016) The Cellular Organization of Zebrafish Visuomotor Circuits. Current biology : CB. 26:R377-R385.
Abstract
Week-old zebrafish execute many complex, visually guided actions using a brain that displays the canonical vertebrate organization, but is less than a cubic millimeter in size. Recent studies have made considerable progress towards understanding the underlying neural circuit basis of these innate responses, at two fundamental levels. Large-scale population recordings have revealed how functional properties and activity dynamics are organized within and across brain regions. Meanwhile, single neurons have been specifically labeled to systematically characterize cell types with distinct morphologies and projection patterns. Combining these approaches, in order to investigate the role of individual, identified neurons in generating neural activity dynamics and behavior, has traditionally been possible only for simple invertebrate systems, but is now becoming feasible in a vertebrate model.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping