PUBLICATION
Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer
- Authors
- Hwang, K.L., Goessling, W.
- ID
- ZDB-PUB-160512-15
- Date
- 2016
- Source
- Advances in experimental medicine and biology 916: 391-410 (Chapter)
- Registered Authors
- Goessling, Wolfram
- Keywords
- Liver cancer, Liver development, Mutations, Pancreas cancer, Pancreas development, Transgenesis, Zebrafish
- MeSH Terms
-
- Animals
- Disease Models, Animal*
- Liver Neoplasms/chemically induced
- Liver Neoplasms/genetics
- Liver Neoplasms/pathology*
- Pancreatic Neoplasms/genetics
- Pancreatic Neoplasms/pathology*
- Zebrafish
- PubMed
- 27165363 Full text @ Adv. Exp. Med. Biol.
Citation
Hwang, K.L., Goessling, W. (2016) Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer. Advances in experimental medicine and biology. 916:391-410.
Abstract
Liver and pancreatic cancers are amongst the leading causes of cancer death. In recent years, genetic and chemical approaches in zebrafish have elucidated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In this chapter, we review the recent approaches and advances in the field to study both hepatocellular carcinomas and pancreatic cancer.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping