PUBLICATION

Blood, blebs and lumen expansion

Authors
Reichman-Fried, M., Raz, E.
ID
ZDB-PUB-160401-17
Date
2016
Source
Nature cell biology   18: 366-7 (Review)
Registered Authors
Raz, Erez, Reichman-Fried, Michal
Keywords
Angiogenesis, Microscopy, Myosin, Zebrafish
MeSH Terms
  • Animals
  • Blood Vessels/embryology*
  • Female
  • Male
  • Morphogenesis*
  • Neovascularization, Physiologic*
PubMed
27027487 Full text @ Nat. Cell Biol.
Citation
Reichman-Fried, M., Raz, E. (2016) Blood, blebs and lumen expansion. Nature cell biology. 18:366-7.
Abstract
A powerful combination of cell labelling, genetic tools and rapid imaging techniques in vivo has now led to a high-resolution description of lumen formation during angiogenesis in zebrafish. The study reveals a haemodynamic-force-driven and myosin-II-dependent cellular mechanism (termed inverse membrane blebbing) as the basis for lumen expansion in unicellular and multicellular angiogenic sprouts.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
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