PUBLICATION
Toxic effects of thifluzamide on zebrafish (Danio rerio)
- Authors
- Yang, Y., Qi, S., Wang, D., Wang, K., Zhu, L., Chai, T., Wang, C.
- ID
- ZDB-PUB-160119-1
- Date
- 2016
- Source
- Journal of hazardous materials 307: 127-136 (Journal)
- Registered Authors
- Keywords
- Enzyme activities, Genes, Histopathology, Mitochondrion, Toxicity
- MeSH Terms
-
- Kidney/drug effects
- Kidney/pathology
- Thiazoles/toxicity*
- Gene Expression
- Succinate Dehydrogenase/metabolism
- Lethal Dose 50
- Zebrafish
- Embryonic Development/drug effects
- Embryo, Nonmammalian
- Larva
- Microscopy, Electron, Transmission
- Animals
- Fungicides, Industrial/toxicity*
- Mitochondria/drug effects
- Mitochondria/ultrastructure
- Liver/drug effects
- Liver/metabolism
- Liver/pathology
- Electron Transport Chain Complex Proteins/metabolism
- Anilides/toxicity*
- Water Pollutants, Chemical/toxicity*
- PubMed
- 26780700 Full text @ J. Hazard. Mater.
Citation
Yang, Y., Qi, S., Wang, D., Wang, K., Zhu, L., Chai, T., Wang, C. (2016) Toxic effects of thifluzamide on zebrafish (Danio rerio). Journal of hazardous materials. 307:127-136.
Abstract
Thifluzamide is a fungicide widely used to control crop diseases, and it therefore constitutes a hazard to the environment. In this study, zebrafish were selected to assess the aquatic toxicity of thifluzamide. The acute and development toxicity of thifluzamide to embryos, larvae, and adult zebrafish were measured and the corresponding 96h-LC50 values were as follows: adult fish (4.19mg/L)
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping