PUBLICATION

Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo

Authors
Zhang, W., Liu, W., Li, P., Kang, J., Wang, J., Wang, H., Tang, B.
ID
ZDB-PUB-150527-7
Date
2015
Source
Chemical communications (Cambridge, England)   51(50): 10150-3 (Other)
Registered Authors
Liu, Wei, Wang, Hui, Zhang, Wei
Keywords
none
MeSH Terms
  • Animals
  • Cell Survival
  • Fluorescent Dyes/chemistry*
  • Hypochlorous Acid/chemistry*
  • Hypochlorous Acid/metabolism*
  • Intracellular Space/metabolism
  • Mice
  • Molecular Imaging/methods*
  • Photons*
  • RAW 264.7 Cells
  • Zebrafish
PubMed
26008174 Full text @ Chem. Commun. (Camb.)
Abstract
Herein, we have developed a novel reversible two-photon fluorescent probe that is well suited for monitoring HOCl levels selectively and instantaneously. Results showed the reversible and instantaneous responses of the probe towards intracellular HOCl. Moreover, the probe was successfully applied to the imaging of the HOCl levels in zebrafish and mice via two-photon imaging.
Genes / Markers
Figures
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Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes