PUBLICATION
Methods for studying the zebrafish brain: past, present and future
- Authors
- Wyatt, C., Bartoszek, E.M., Yaksi, E.
- ID
- ZDB-PUB-150423-5
- Date
- 2015
- Source
- The European journal of neuroscience 42(2): 1746-63 (Review)
- Registered Authors
- Wyatt, Cameron, Yaksi, Emre
- Keywords
- CRISPR, Cre Lox, Gal4, behavior, calcium imaging, chemical screens, genetic screens, genome editing, mutagenesis, neural circuits, neuroscience, optogenetics, regeneration, transgenic, zebrafish
- MeSH Terms
-
- History, 20th Century
- Morpholinos/pharmacology
- Molecular Biology*/history
- Molecular Biology*/methods
- Molecular Biology*/trends
- Brain/physiology*
- Gene Expression Regulation/genetics
- Zebrafish/anatomy & histology*
- Neurosciences*/history
- Neurosciences*/methods
- Neurosciences*/trends
- RNA, Messenger/genetics
- RNA, Messenger/metabolism
- Mutagenesis
- DNA/genetics
- DNA/metabolism
- History, 21st Century
- Animals
- PubMed
- 25900095 Full text @ Eur. J. Neurosci.
Citation
Wyatt, C., Bartoszek, E.M., Yaksi, E. (2015) Methods for studying the zebrafish brain: past, present and future. The European journal of neuroscience. 42(2):1746-63.
Abstract
The zebrafish (Danio rerio) is one of the most promising new model organisms. The increasing popularity of this amazing small vertebrate is evident from the exponentially growing numbers of research articles, funded projects and new discoveries associated with the use of zebrafish for studying development, brain function, human diseases and screening for new drugs. Thanks to the development of novel technologies, the range of zebrafish research is constantly expanding with new tools synergistically enhancing traditional techniques. In this review we will highlight the past and present techniques which have made, and continue to make, zebrafish an attractive model organism for various fields of biology, with a specific focus on neuroscience. This article is protected by copyright. All rights reserved.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping