ZFIN ID: ZDB-PUB-141211-5
Topographic wiring of the retinotectal connection in zebrafish
Kita, E.M., Scott, E.K., Goodhill, G.J.
Date: 2015
Source: Developmental Neurobiology   75(6): 542-56 (Review)
Registered Authors: Scott, Ethan
Keywords: none
MeSH Terms:
  • Animals
  • Retina/physiology*
  • Superior Colliculi/physiology*
  • Visual Pathways/physiology*
  • Zebrafish*/anatomy & histology
  • Zebrafish*/physiology
PubMed: 25492632 Full text @ Dev. Neurobiol.
The zebrafish retinotectal projection provides an attractive model system for studying many aspects of topographic map formation and maintenance. Visual connections initially start to form between three and five days post fertilization, and remain plastic throughout the life of the fish. Zebrafish are easily manipulated surgically, genetically and chemically, and a variety of molecular tools exist to enable visualization and control of various aspects of map development. Here we review zebrafish retinotectal map formation, focusing particularly on the detailed structure and dynamics of the connections, the molecules that are important in map creation, and how activity regulates the maintenance of the map. This article is protected by copyright. All rights reserved.