PUBLICATION
The teleost agouti-related protein 2 gene is an ohnolog gone missing from the tetrapod genome
- Authors
- Braasch, I., and Postlethwait, J.H.
- ID
- ZDB-PUB-140903-24
- Date
- 2011
- Source
- Proceedings of the National Academy of Sciences of the United States of America 108(13): E47-E48 (Journal)
- Registered Authors
- Braasch, Ingo, Postlethwait, John H.
- Keywords
- none
- MeSH Terms
-
- Agouti-Related Protein/genetics*
- Animals
- Biological Evolution
- Fishes/genetics*
- Gene Duplication
- Genome*
- Protein Isoforms/genetics*
- PubMed
- 21406593 Full text @ Proc. Natl. Acad. Sci. USA
Citation
Braasch, I., and Postlethwait, J.H. (2011) The teleost agouti-related protein 2 gene is an ohnolog gone missing from the tetrapod genome. Proceedings of the National Academy of Sciences of the United States of America. 108(13):E47-E48.
Abstract
A central question in evolutionary genomics is how morphological differences between taxa arise from differences in gene repertoire. Answers require rigorous orthology assignments. Recent work (1) illuminated the mechanism of background adaptation in teleost fishes by investigating the function of agouti-related protein 2 (agrp2), a gene so far found only in teleosts.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping