PUBLICATION
From fish tank to bedside in cancer therapy: an interview with Leonard Zon
- Authors
- Zon, L., Cagan, R.
- ID
- ZDB-PUB-140808-10
- Date
- 2014
- Source
- Disease models & mechanisms 7: 735-8 (Other)
- Registered Authors
- Zon, Leonard I.
- Keywords
- none
- MeSH Terms
-
- Animals
- Disease Models, Animal
- History, 20th Century
- History, 21st Century
- Humans
- Neoplasms/history*
- Neoplasms/therapy*
- Translational Research, Biomedical*
- United States
- Zebrafish/metabolism*
- PubMed
- 24973742 Full text @ Dis. Model. Mech.
Citation
Zon, L., Cagan, R. (2014) From fish tank to bedside in cancer therapy: an interview with Leonard Zon. Disease models & mechanisms. 7:735-8.
Abstract
Leonard Zon, who is based at Harvard Medical School, is internationally recognized for his pioneering work in hematology and stem cell biology. His lab uses zebrafish as a model to understand blood cell development and, in recent years, has made inspiring breakthroughs in the treatment of blood diseases and cancer, helping to establish zebrafish as a powerful model for translational research. In this interview, Leonard speaks to Disease Models & Mechanisms Editor-in-Chief, Ross Cagan, about the evolution of his career from developmental biologist to physician-scientist and the stories behind some of his major research accomplishments. He also discusses challenges and opportunities in zebrafish research and provides advice on translating basic research findings to the clinic.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping