PUBLICATION

Cell migration: sinking in a gradient

Authors
Moissoglu, K., Majumdar, R., and Parent, C.A.
ID
ZDB-PUB-140317-8
Date
2014
Source
Current biology : CB   24(1): R23-R25 (Other)
Registered Authors
Keywords
none
MeSH Terms
  • Animals
  • Cell Movement/physiology*
  • Chemotactic Factors/metabolism*
  • Humans
  • Lateral Line System/embryology*
  • Receptors, CXCR/metabolism*
  • Zebrafish/embryology*
  • Zebrafish/physiology*
  • Zebrafish Proteins/metabolism*
PubMed
24405672 Full text @ Curr. Biol.
Abstract

How chemoattractant gradients form and persist in complex tissues is a key question in cell migration. Two studies now show that CXCR7 acts as a sink in the migrating zebrafish lateral line primordium to generate SDF1 gradients.

Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping