PUBLICATION

Of fish and men: using zebrafish to fight human diseases

Authors
Ablain, J., and Zon, L.I.
ID
ZDB-PUB-140113-3
Date
2013
Source
Trends in cell biology   23(12): 584-586 (Review)
Registered Authors
Zon, Leonard I.
Keywords
none
MeSH Terms
  • Animals
  • Disease*
  • Disease Models, Animal*
  • Humans
  • Translational Research, Biomedical
  • Zebrafish/physiology*
PubMed
24275383 Full text @ Trends Cell Biol.
Abstract

Long restricted to the field of developmental biology, the use of the zebrafish (Danio rerio) has extended to the study of human pathogenesis. Fostered by the rapid adaptation of new technologies, the design and analysis of fish models of human diseases have contributed important findings that are now making their way from aquariums to clinics. Here we outline the clinical relevance of the zebrafish as a model organism.

Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping