PUBLICATION
Inter-individual and inter-strain variations in zebrafish locomotor ontogeny
- Authors
- Lange, M., Neuzeret, F., Fabreges, B., Froc, C., Bedu, S., Bally-Cuif, L., and Norton, W.H.
- ID
- ZDB-PUB-130904-1
- Date
- 2013
- Source
- PLoS One 8(8): e70172 (Journal)
- Registered Authors
- Bally-Cuif, Laure, Bedu, Sebastien, Lange, Merlin, Norton, Will
- Keywords
- Biological locomotion, Swimming, Fishes, Zebrafish, Animal behavior, Larvae, Fertilization, Morphogenesis
- MeSH Terms
-
- Male
- Genetic Variation/physiology*
- Swimming/physiology
- Female
- Animals
- Zebrafish/physiology*
- Behavior, Animal/physiology
- Analysis of Variance
- Larva/physiology*
- Locomotion/physiology*
- PubMed
- 23950910 Full text @ PLoS One
Citation
Lange, M., Neuzeret, F., Fabreges, B., Froc, C., Bedu, S., Bally-Cuif, L., and Norton, W.H. (2013) Inter-individual and inter-strain variations in zebrafish locomotor ontogeny. PLoS One. 8(8):e70172.
Abstract
Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the locomotion parameters of six common zebrafish strains from two different laboratories to determine the stability and repeatability of these behaviours. Our results demonstrate large variability in locomotion and fast swim events between strains and between laboratories across time. These data highlight the necessity for careful, strain-specific controls when analysing locomotor phenotypes and open up the possibility of standardising the quantification of zebrafish behaviour at multiple life stages.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping