Toxic effects of copper ion in zebrafish in the joint presence of CdTe QDs
- Authors
- Zhang, W., Miao, Y., Lin, K., Chen, L., Dong, Q., and Huang, C.
- ID
- ZDB-PUB-130309-1
- Date
- 2013
- Source
- Environmental pollution (Barking, Essex : 1987) 176C: 158-164 (Journal)
- Registered Authors
- Zhang, Wei
- Keywords
- quantum dots, heavy metal, zebrafish, facilitated transport, toxicological effect
- MeSH Terms
-
- Animals
- Cadmium Compounds/toxicity*
- Copper/toxicity*
- Quantum Dots*
- Risk Assessment
- Tellurium/toxicity*
- Toxicity Tests
- Water Pollutants, Chemical/toxicity*
- Zebrafish
- PubMed
- 23421984 Full text @ Environ. Pollut.
Quantum dots (QDs) have strong adsorption capacity; therefore, their potential toxicity of the facilitated transport of other trace toxic pollutants when they co-exist to aquatic organisms has become a hot research topic. The lab study was performed to determine the developmental toxicities to the zebrafish after exposed to the combined pollution of Cadmium-telluride (CdTe) QDs and copper ion (Cu2+) compared to the single exposure. Our findings for the first time revealed that: 1) CdTe QDs facilitated the accumulation of Cu2+ in zebrafish, 2) the higher mortality, lower hatch rate, and more malformations can be clearly observed, 3) the diverse vascular hyperplasia, turbulence, and bifurcation of the exposed FLI-1 transgenic zebrafish larvae appeared together, 4) the synergistic effects played more important role during joint exposure. These observations provide a basic understanding of CdTe QDs and Cu2+ joint toxicity to aquatic organisms.