PUBLICATION

Brain regionalisation: Of signalling centres and boundaries

Authors
Cavodeassi, F., and Houart, C.
ID
ZDB-PUB-110629-21
Date
2012
Source
Developmental Neurobiology   72(3): 218-233 (Review)
Registered Authors
Cavodeassi, Florencia, Houart, Corinne
Keywords
brain, CNS, neural plate, local organisers, signalling centres, morphogens, pattern formation, fate specification
MeSH Terms
  • Animals
  • Brain/embryology
  • Brain/growth & development*
  • Cell Communication/physiology*
  • Humans
  • Morphogenesis/physiology
  • Signal Transduction/physiology*
  • Transcription, Genetic/physiology
  • Zebrafish
PubMed
21692189 Full text @ Dev. Neurobiol.
Abstract
Our knowledge of the general mechanisms controlling the formation of the vertebrate central nervous system has advanced tremendously in the last decade. Here, we discuss the impact of the combined use of cell manipulation, in vivo imaging and genetics in the zebrafish on recent progress in understanding how signalling processes progressively control regionalisation of the central nervous system. We highlight the unresolved issues and speculate upon the fundamental role the zebrafish will continue having in answering them.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping