PUBLICATION
DNA methylation in zebrafish
- Authors
- Goll, M.G., and Halpern, M.E.
- ID
- ZDB-PUB-110518-26
- Date
- 2011
- Source
- Progress in molecular biology and translational science 101: 193-218 (Chapter)
- Registered Authors
- Goll, Mary, Halpern, Marnie E.
- Keywords
- none
- MeSH Terms
-
- Animals
- DNA Methylation*
- Zebrafish/genetics*
- PubMed
- 21507352 Full text @ Prog. Mol. Biol. Transl. Sci.
Citation
Goll, M.G., and Halpern, M.E. (2011) DNA methylation in zebrafish. Progress in molecular biology and translational science. 101:193-218.
Abstract
DNA methylation is crucial for normal development and cellular differentiation in many large-genome eukaryotes. The small tropical freshwater fish Danio rerio (zebrafish) has recently emerged as a powerful system for the study of DNA methylation, especially in the context of development. This review summarizes our current knowledge of DNA methylation in zebrafish and provides evidence for the general conservation of this system with mammals. In addition, emerging strategies are highlighted that use the fish model to address some of the key unanswered questions in DNA methylation research.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping