PUBLICATION
Novel experimental models and paradigms for neuropsychiatric disorders: Editorial
- Authors
- Kalueff, A.V., and Schmidt, M.V.
- ID
- ZDB-PUB-110103-22
- Date
- 2011
- Source
- Progress in neuro-psychopharmacology & biological psychiatry 35(6): 1355-1356 (Other)
- Registered Authors
- Kalueff, Allan V.
- Keywords
- animal models, behavior, anxiety, zebrafish, rodents, marmosets, neuropsychiatric disorders
- MeSH Terms
-
- Animals
- Brain Diseases*
- Disease Models, Animal*
- Humans
- Mental Disorders*
- Research Design*
- Translational Research, Biomedical/methods*
- PubMed
- 21184793 Full text @ Prog. Neuropsychopharmacol. Biol. Psychiatry
Citation
Kalueff, A.V., and Schmidt, M.V. (2011) Novel experimental models and paradigms for neuropsychiatric disorders: Editorial. Progress in neuro-psychopharmacology & biological psychiatry. 35(6):1355-1356.
Abstract
The increase in prevalance of neuropsychiatric disorders necessitates the development and integration of novel experimental approaches to investigate complex pathologies. In this Special Issue, we discuss currently used animal models of brain disorders, and focus on the improvement and integration of modern methods as well as development of new paradigms to advance research in neuroscience. Further, we emphasize the importance of new technical and conceptual approaches to derive more translatable information from experimental models of pathogenesis. Contributions address use of several different animal (e.g., rodent, zebrafish, marmoset) models focusing on diverse but related phenomena, to better characterize behavioral repetoires and improve the validity of behavioral paradigms. Overall, this Issue covers a wide-spectrum of paradigms, focusing on the advancement of animal models of neuropsychiatric disorders through improvement of methods and integration of novel approaches.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping