PUBLICATION
Advancements on the zebrafish glioma model
- Authors
- Li, D., Peng, K., Li, Y., and Peng, Y.
- ID
- ZDB-PUB-100601-23
- Date
- 2010
- Source
- Chinese journal of cancer 29(6): 621-625 (Review)
- Registered Authors
- Peng, Kou, Peng, Ying
- Keywords
- Zebrafish, glioma, model
- MeSH Terms
-
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Brain Neoplasms*/chemically induced
- Brain Neoplasms*/genetics
- Brain Neoplasms*/pathology
- Carcinogens
- Disease Models, Animal*
- Genome
- Glioma*/chemically induced
- Glioma*/genetics
- Glioma*/pathology
- Mutagenesis, Insertional
- Mutation*
- Neoplasm Transplantation
- Zebrafish/genetics*
- PubMed
- 20507736 Full text @ Chin. J. Cancer
Citation
Li, D., Peng, K., Li, Y., and Peng, Y. (2010) Advancements on the zebrafish glioma model. Chinese journal of cancer. 29(6):621-625.
Abstract
Glioma derived from the neural ectoderm is the most common brain tumor and is of great damage to human health among all lethal tumors. Scientists have been trying their best to find new methods and develop new drugs to treat glioma in recent years. The animal glioma model is of great importance to the research. Researchers have developed many animal glioma models, like the rat and mouse model. Now we are trying to develop a new zebrafish glioma model, which has much more advantages and fewer disadvantages than the traditional models in regard to gene mutation, chemical induction, and xenografts. Establishing a glioma model in zebrafish is feasible and would be of great use to patients with this common brain tumor.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping