|ZFIN ID: ZDB-PUB-100420-32|
Oligonucleotide-Based Tools for Studying Zebrafish Development
Shestopalov, I.A., and Chen, J.K.
|Source:||Zebrafish 7(1): 31-40 (Review)|
|Registered Authors:||Chen, James K., Shestopalov, Ilya|
|PubMed:||20392138 Full text @ Zebrafish|
Shestopalov, I.A., and Chen, J.K. (2010) Oligonucleotide-Based Tools for Studying Zebrafish Development. Zebrafish. 7(1):31-40.
ABSTRACTSynthetic and nonnatural oligonucleotides have been used extensively to interrogate gene function in zebrafish. In this review, we survey the capabilities and limitations of various oligonucleotide-based technologies for perturbing RNA function and tracking RNA expression. We also examine recent strategies for achieving spatiotemporal control of oligonucleotide function, particularly light-gated technologies that exploit the optical transparency of zebrafish embryos.
ADDITIONAL INFORMATION No data available