PUBLICATION
Organization and physiology of posterior lateral line afferent neurons in larval zebrafish
- Authors
- Liao, J.C.
- ID
- ZDB-PUB-100302-9
- Date
- 2010
- Source
- Biology letters 6(3): 402-405 (Journal)
- Registered Authors
- Keywords
- lateral line ganglion, zebrafish, afferent neuron, electrophysiology, neuromast, hydrodynamics
- MeSH Terms
-
- Animals
- Biomechanical Phenomena
- Larva/anatomy & histology
- Larva/physiology
- Models, Biological
- Motor Activity/physiology
- Nervous System/anatomy & histology
- Nervous System Physiological Phenomena
- Neurons, Afferent/physiology*
- Neurons, Afferent/ultrastructure
- Patch-Clamp Techniques
- Swimming/physiology
- Zebrafish/anatomy & histology*
- Zebrafish/physiology
- PubMed
- 20181553 Full text @ Biol. Lett.
Citation
Liao, J.C. (2010) Organization and physiology of posterior lateral line afferent neurons in larval zebrafish. Biology letters. 6(3):402-405.
Abstract
The lateral line system of larval zebrafish can translate hydrodynamic signals from the environment to guide body movements. Here, I demonstrate a spatial relationship between the organization of afferent neurons in the lateral line ganglion and the innervation of neuromasts along the body. I developed a whole cell patch clamp recording technique to show that afferents innervate multiple direction-sensitive neuromasts, which are sensitive to low fluid velocities. This work lays the foundation to integrate sensory neuroscience and the hydrodynamics of locomotion in a model genetic system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping