PUBLICATION
Lbx1 expression and frog limb development
- Authors
- Sabo, M.C., Nath, K., and Elinson, R.P.
- ID
- ZDB-PUB-100126-11
- Date
- 2009
- Source
- Development genes and evolution 219(11-12): 609-612 (Journal)
- Registered Authors
- Keywords
- Direct development, Eleutherodactylus coqui, Muscle, leg, Somite, Anuran amphibian
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Anura/anatomy & histology
- Anura/embryology*
- Cloning, Molecular
- DNA Primers/genetics
- Embryo, Nonmammalian/anatomy & histology
- Extremities/anatomy & histology
- Extremities/embryology*
- Gene Expression Regulation, Developmental/physiology*
- Hawaii
- Homeodomain Proteins/genetics
- Homeodomain Proteins/metabolism*
- In Situ Hybridization
- Molecular Sequence Data
- Phylogeny
- Puerto Rico
- Somites/metabolism*
- Spinal Cord/metabolism
- PubMed
- 20091319 Full text @ Dev. Genes Evol.
Citation
Sabo, M.C., Nath, K., and Elinson, R.P. (2009) Lbx1 expression and frog limb development. Development genes and evolution. 219(11-12):609-612.
Abstract
In order to identify prospective limb muscle cells in a frog, we cloned Lbx1 from the direct developing frog Eleutherodactylus coqui. Like in embryos of the frog Xenopus laevis but unlike in other vertebrates, EcLbx1 is expressed in all trunk somites. Like in embryos of chick, mouse, and zebrafish, cells expressing EcLbx1 are then found in limb buds, consistent with migration of those cells from somites. EcLbx1 is also expressed in the dorsal spinal cord as in other vertebrates.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping