PUBLICATION
Vascular morphogenesis in the zebrafish embryo
- Authors
- Ellertsdóttir, E., Lenard, A., Blum, Y., Krudewig, A., Herwig, L., Affolter, M., and Belting, H.G.
- ID
- ZDB-PUB-091120-29
- Date
- 2010
- Source
- Developmental Biology 341(1): 56-65 (Review)
- Registered Authors
- Affolter, Markus
- Keywords
- Angiogenesis, Vasculogenesis, Branching morphogenesis, Cell migration, Lumen formation, Development, Zebrafish
- MeSH Terms
-
- Animals
- Blood Vessels/embryology*
- Embryo, Nonmammalian/metabolism
- Morphogenesis*
- Zebrafish/embryology*
- PubMed
- 19895803 Full text @ Dev. Biol.
Citation
Ellertsdóttir, E., Lenard, A., Blum, Y., Krudewig, A., Herwig, L., Affolter, M., and Belting, H.G. (2010) Vascular morphogenesis in the zebrafish embryo. Developmental Biology. 341(1):56-65.
Abstract
During embryonic development, the vertebrate vasculature is undergoing vast growth and remodeling. Blood vessels can be formed by a wide spectrum of different morphogenetic mechanisms, such as budding, cord hollowing, cell hollowing, cell wrapping and intussusception. Here, we describe the vascular morphogenesis that occurs in the early zebrafish embryo. We discuss the diversity of morphogenetic mechanisms that contribute to vessel assembly, angiogenic sprouting and tube formation in different blood vessels and how some of these complex cell behaviors are regulated by molecular pathways.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping