PUBLICATION
Zebrafish Pancreas Development
- Authors
- Tiso, N., Moro, E., and Argenton, F.
- ID
- ZDB-PUB-090601-17
- Date
- 2009
- Source
- Molecular and Cellular Endocrinology 312(1-2): 24-30 (Review)
- Registered Authors
- Argenton, Francesco, Moro, Enrico, Tiso, Natascia
- Keywords
- none
- MeSH Terms
-
- Whole Body Imaging/methods
- Cell Differentiation
- Models, Animal*
- Genomics/methods
- Morphogenesis
- Regeneration
- Animals
- Pancreas/embryology*
- Pancreas/growth & development
- Pancreas/physiology
- Zebrafish/embryology*
- Zebrafish/genetics
- Zebrafish/growth & development
- PubMed
- 19477220 Full text @ Mol. Cell. Endocrinol.
Citation
Tiso, N., Moro, E., and Argenton, F. (2009) Zebrafish Pancreas Development. Molecular and Cellular Endocrinology. 312(1-2):24-30.
Abstract
An accurate understanding of the molecular events governing pancreas development can have an impact on clinical medicine related to diabetes, obesity and pancreatic cancer, diseases with a high impact in public health. Until 1996, the main animal models in which pancreas formation and differentiation could be studied were mouse and, for some instances related to early development, chicken and Xenopus. Zebrafish has penetrated this field very rapidly offering a new model of investigation; by joining functional genomics, genetics and in vivo whole mount visualization, Danio rerio has allowed large scale and fine multidimensional analysis of gene functions during pancreas formation and differentiation.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping