PUBLICATION

Preparing for a Semiannual IACUC Inspection of a Satellite Zebrafish (Danio rerio) Facility

Authors
Koerber, A.S., and Kalishman, J.
ID
ZDB-PUB-090302-29
Date
2009
Source
Journal of the American Association for Laboratory Animal Science : JAALAS   48(1): 65-75 (Journal)
Registered Authors
Koerber, Amy
Keywords
GAC, GRANULAR ACTIVATED CARBON, IACUC, INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE, MS222, 3-AMINOBENZOIC ACID ETHYL ESTER (TRICAINE), RO, REVERSE OSMOSIS, SOP, STANDARD OPERATING PROCEDURES, SPF, SPECIFIC PATHOGEN-FREE
MeSH Terms
  • Animal Care Committees*
  • Animal Husbandry/legislation & jurisprudence
  • Animal Husbandry/standards*
  • Animal Welfare/legislation & jurisprudence
  • Animal Welfare/standards*
  • Animals
  • Animals, Laboratory
  • Cooperative Behavior
  • Female
  • Laboratory Animal Science/legislation & jurisprudence
  • Laboratory Animal Science/standards*
  • Male
  • Records
  • Zebrafish/physiology*
PubMed
19245754
Abstract
Institutions worldwide have experienced a rapid growth in the use of zebrafish as a research model for a variety of molecular and genetic studies of vertebrate development. This expansion in zebrafish research essentially has outpaced the establishment of specific recommendations for the care and use of fish in research. In some cases, this situation has created a dilemma where an Institutional Animal Care and Use Committee, which is responsible for oversight of vertebrate animal research, is not fully prepared to undertake this role for a decentralized zebrafish facility. IACUC inspectors will be more equipped to ask pertinent questions by understanding the basic principles of zebrafish health and facility management. Concurrently, zebrafish facility managers can contribute to the progress of a semiannual facility inspection by maintaining fully accessible operating records. In the context of presenting a well-established and useful model of zebrafish management and recordkeeping to the zebrafish facility operator, the information we present here also prepares a potential IACUC inspector to conduct a constructive and positive inspection.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping