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ZFIN ID: ZDB-PUB-081124-1
Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development
Stenkamp, D.L.
Date: 2008
Source: Molecular Biology Intelligence Unit : 56-68 (Chapter)
Registered Authors: Stenkamp, Deborah L.
Keywords: none
MeSH Terms: none
PubMed: none Full text @ Mol. Biol. Int. Unit
The Hedgehog signalling pathway is important in a large number of developmental contexts. In this review, several functions of this pathway for vertebrate eye formation and differentiation will be discussed, with an emphasis on information derived from the zebrafish model. The highlighted roles for Hedgehog signalling include those in photoreceptor development, ganglion cell development, retinal cell proliferation and cell death, and the initiation of retinal neurogenesis.