PUBLICATION

Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development

Authors
Stenkamp, D.L.
ID
ZDB-PUB-081124-1
Date
2008
Source
Molecular Biology Intelligence Unit : 56-68 (Chapter)
Registered Authors
Stenkamp, Deborah L.
Keywords
none
MeSH Terms
none
PubMed
none Full text @ Mol. Biol. Int. Unit
Abstract
The Hedgehog signalling pathway is important in a large number of developmental contexts. In this review, several functions of this pathway for vertebrate eye formation and differentiation will be discussed, with an emphasis on information derived from the zebrafish model. The highlighted roles for Hedgehog signalling include those in photoreceptor development, ganglion cell development, retinal cell proliferation and cell death, and the initiation of retinal neurogenesis.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping