ZFIN ID: ZDB-PUB-080327-5
Gene regulation technologies in zebrafish
Esengil, H., and Chen, J.K.
Date: 2008
Source: Molecular Biosystems   4(4): 300-308 (Review)
Registered Authors: Chen, James K.
Keywords: none
MeSH Terms:
  • Animals
  • Gene Expression Regulation/physiology*
  • Genetic Engineering*
  • Zebrafish/genetics*
  • Zebrafish/metabolism*
  • Zebrafish Proteins/genetics
  • Zebrafish Proteins/metabolism
PubMed: 18354783 Full text @ Mol. Biosyst.
ABSTRACT
Achieving the potential of zebrafish models in biomedical research is contingent on the development of reverse-genetic resources. This review describes current technologies for genetic perturbations in zebrafish, including an ecdysone receptor-based system that permits conditional transgene expression. Such methodologies promise to enable new zebrafish models for interrogating human physiology and disease.
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