|ZFIN ID: ZDB-PUB-080327-5|
Gene regulation technologies in zebrafish
Esengil, H., and Chen, J.K.
|Source:||Molecular Biosystems 4(4): 300-308 (Review)|
|Registered Authors:||Chen, James K.|
|PubMed:||18354783 Full text @ Mol. Biosyst.|
Esengil, H., and Chen, J.K. (2008) Gene regulation technologies in zebrafish. Molecular Biosystems. 4(4):300-308.
ABSTRACTAchieving the potential of zebrafish models in biomedical research is contingent on the development of reverse-genetic resources. This review describes current technologies for genetic perturbations in zebrafish, including an ecdysone receptor-based system that permits conditional transgene expression. Such methodologies promise to enable new zebrafish models for interrogating human physiology and disease.
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