PUBLICATION
Developmental Biology: Micro(RNA)-Managing Nodal
- Authors
- Martin, B.L., and Kimelman, D.
- ID
- ZDB-PUB-071125-26
- Date
- 2007
- Source
- Current biology : CB 17(22): R975--R977 (Journal)
- Registered Authors
- Kimelman, David
- Keywords
- none
- MeSH Terms
-
- MicroRNAs/physiology*
- Humans
- Signal Transduction/genetics
- Signal Transduction/physiology*
- Embryo, Nonmammalian/physiology*
- Nodal Protein
- Transforming Growth Factor beta/antagonists & inhibitors
- Transforming Growth Factor beta/biosynthesis
- Transforming Growth Factor beta/genetics
- Transforming Growth Factor beta/physiology*
- Animals
- Body Patterning/genetics
- Body Patterning/physiology*
- PubMed
- 18029256 Full text @ Curr. Biol.
Citation
Martin, B.L., and Kimelman, D. (2007) Developmental Biology: Micro(RNA)-Managing Nodal. Current biology : CB. 17(22):R975--R977.
Abstract
Nodal signaling plays an essential role during the induction and patterning of vertebrate embryonic tissue types. In Xenopus and zebrafish, microRNAs regulate Nodal signaling, but surprisingly by very different mechanisms.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping