PUBLICATION
Comparison of the acute toxicity for gamma-cyhalothrin and lambda-cyhalothrin to zebra fish and shrimp
- Authors
- Wang, W., Cai, D.J., Shan, Z.J., Chen, W.L., Poletika, N., and Gao, X.W.
- ID
- ZDB-PUB-061222-17
- Date
- 2007
- Source
- Regulatory toxicology and pharmacology : RTP 47(2): 184-188 (Journal)
- Registered Authors
- Keywords
- Gamma-cyhalothrin, Lambda-cyhalothrin, Isomer, Toxicity, Aquatic, Fish, Shrimp, Rice
- MeSH Terms
-
- Animals
- Dose-Response Relationship, Drug
- Insecticides/toxicity*
- Lethal Dose 50
- Nitriles/chemistry
- Nitriles/toxicity*
- Palaemonidae/metabolism*
- Pyrethrins/chemistry
- Pyrethrins/toxicity*
- Stereoisomerism
- Toxicity Tests, Acute
- Zebrafish/metabolism*
- PubMed
- 17052827 Full text @ Regul. Toxicol. Pharmacol.
Citation
Wang, W., Cai, D.J., Shan, Z.J., Chen, W.L., Poletika, N., and Gao, X.W. (2007) Comparison of the acute toxicity for gamma-cyhalothrin and lambda-cyhalothrin to zebra fish and shrimp. Regulatory toxicology and pharmacology : RTP. 47(2):184-188.
Abstract
Gamma-cyhalothrin 15CS (GCH) contains only the active stereoisomer of the two isomers found in lambda-cyhalothrin 25EW (LCH). GCH (0.5xrate) provides equivalent overall insect control as LCH (1xrate). Both formulations showed high acute toxicity to zebra fish (Brachydanio rerio H.B.) and shrimp (Macrobrachium nippoensis de Haan). The 96-h LC(50(zebra fish,GCH)) is 1.93mug a.i/L and LC(50(zebra fish,LCH)) is 1.94mug a.i/L. LC(50(shrimp,GCH)) is 0.28mug a.i./L and LC(50(shrimp,LCH)) 0.04mug a.i./L. This indicates that the toxicity to shrimp is likely stereochemistry-dependent. The fates of GCH and LCH are similar in laboratory simulated rice paddy water and their concentrations decrease rapidly, with no GCH or LCH detected after 3 or 4 days. Both are toxic to shrimp in a simulated paddy irrigation reservoir even though treated return water is diluted 5 times. No shrimp fatality is shown in the GCH-treated paddy water after a 4-day holding period, and longer than 5 days is necessary to reach a zero fatality rate for LCH. This is compatible with the 7-day water holding period considered reasonable in agricultural practice.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping