PUBLICATION
RNA of AmVegT, the axolotl orthologue of the Xenopus meso-endodermal determinant, is not localized in the oocyte
- Authors
- Nath, K., and Elinson, R.P.
- ID
- ZDB-PUB-060825-14
- Date
- 2007
- Source
- Gene expression patterns : GEP 7(1-2): 197-201 (Journal)
- Registered Authors
- Keywords
- Urodele, Anuran, Amphibian, Axolotl, Ambystoma, Mesoderm, Mesodermal determinant, VegT, Transcription factor, Localized RNA, T-box, Oocyte, Gastrula, Rohon-Beard neuron, Tailbud
- MeSH Terms
-
- Oocytes/metabolism
- Xenopus laevis/embryology
- Xenopus laevis/genetics
- Xenopus laevis/metabolism
- Base Sequence
- Gene Expression Regulation, Developmental
- T-Box Domain Proteins/genetics*
- T-Box Domain Proteins/metabolism
- DNA Primers/genetics
- Ambystoma mexicanum/embryology*
- Ambystoma mexicanum/genetics*
- Ambystoma mexicanum/metabolism
- RNA/genetics
- RNA/metabolism
- Xenopus Proteins/genetics
- Xenopus Proteins/metabolism
- Animals
- Cloning, Molecular
- Female
- Species Specificity
- PubMed
- 16920404 Full text @ Gene Expr. Patterns
Citation
Nath, K., and Elinson, R.P. (2007) RNA of AmVegT, the axolotl orthologue of the Xenopus meso-endodermal determinant, is not localized in the oocyte. Gene expression patterns : GEP. 7(1-2):197-201.
Abstract
The transcription factor, VegT, is the meso-endodermal determinant in Xenopus laevis, and the localization of VegT RNA to the vegetal cortex of the oocyte is an important starting point for embryonic patterning. We have cloned the VegT orthologue from the urodele amphibian, Ambystoma mexicanum, the Mexican axolotl. Axolotl VegT (AmVegT) is expressed zygotically in the presumptive mesoderm and Rohon-Beard neurons as in X. laevis, and its expression persists at the tip of the tail as with zebrafish and chicken orthologues. Unlike in X. laevis, AmVegT RNA is not localized in the oocyte. This result highlights a major difference in the molecular organization of oocytes of these two amphibian orders.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping