ZFIN ID: ZDB-PUB-060816-8
Precious metal economy
Merchant, S.S., and Sagasti, A.
Date: 2006
Source: Cell Metabolism   4(2): 99-101 (Journal)
Registered Authors: Sagasti, Alvaro
Keywords: none
MeSH Terms:
  • Animals
  • Copper/metabolism*
  • Disease Models, Animal
  • Humans
  • Menkes Kinky Hair Syndrome/etiology
  • Menkes Kinky Hair Syndrome/genetics*
  • Menkes Kinky Hair Syndrome/metabolism*
  • Zebrafish
PubMed: 16890535 Full text @ Cell Metab.
ABSTRACT
The zebrafish is emerging as a system of choice for modeling human disease. In this issue of Cell Metabolism, describe a model for Menkes disease, a genetic disorder in copper utilization. Using genetic and chemical screens, the authors highlight the impact of maternal nutrition on embryo development. The work reveals a hierarchy of temporal and dosage-dependent phenotypes for copper nutrition.
ADDITIONAL INFORMATION No data available