PUBLICATION
Zebrafish z-otu, a novel Otu and Tudor domain-containing gene, is expressed in early stages of oogenesis and embryogenesis
- Authors
- Mo, S., Song, P., Lv, D., Chen, Y., Zhou, W., Gong, W., and Zhu, Z.
- ID
- ZDB-PUB-060216-1
- Date
- 2005
- Source
- BBA Gene Structure and Expression 1732(1-3): 1-7 (Journal)
- Registered Authors
- Song, Ping, Zhou, Wei
- Keywords
- Z-otu, Otu domain, Tudor domain, Oogenesis, Embryogenesis, Zebrafish
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Cysteine Endopeptidases/chemistry
- Cysteine Endopeptidases/genetics*
- Embryo, Nonmammalian/cytology
- Embryonic Development/genetics*
- Exons/genetics
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Developmental*
- Introns/genetics
- Molecular Sequence Data
- Oogenesis/genetics*
- Ovary/cytology
- Protein Structure, Tertiary
- RNA, Messenger/genetics
- RNA, Messenger/metabolism
- Sequence Alignment
- Zebrafish/embryology*
- Zebrafish/genetics*
- Zebrafish Proteins/chemistry
- Zebrafish Proteins/genetics*
- PubMed
- 16469398 Full text @ BBA Gene Structure and Expression
Citation
Mo, S., Song, P., Lv, D., Chen, Y., Zhou, W., Gong, W., and Zhu, Z. (2005) Zebrafish z-otu, a novel Otu and Tudor domain-containing gene, is expressed in early stages of oogenesis and embryogenesis. BBA Gene Structure and Expression. 1732(1-3):1-7.
Abstract
Several studies have suggested that Otu domain had de-ubiquitinating activity and Tudor domain was important for the formation of germ cells. Here, we reported a novel zebrafish ovary-specific gene containing Otu and Tudor domain, z-otu, which was expressed at stages I-III oocytes and embryonic stages from zygotes to early blastula during embryonic cells maintained their totipotency. Therefore, z-otu might link the ubiquitin signaling pathway to early oogenesis and maintaining the totipotency of embryonic cell.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping