PUBLICATION
Endoderm development in vertebrates: fate mapping, induction and regional specification
- Authors
- Fukuda, K., and Kikuchi, Y.
- ID
- ZDB-PUB-050823-4
- Date
- 2005
- Source
- Development, growth & differentiation 47(6): 343-355 (Review)
- Registered Authors
- Kikuchi, Yutaka
- Keywords
- endoderm, fate mapping, induction, regional specification
- MeSH Terms
-
- Animals
- Cell Differentiation
- Chick Embryo
- Ectoderm/cytology
- Ectoderm/physiology
- Embryonic Induction
- Endoderm/cytology
- Endoderm/physiology*
- Mesoderm/cytology
- Mesoderm/physiology
- Mice
- Vertebrates/embryology*
- Xenopus
- Zebrafish/embryology
- PubMed
- 16109032 Full text @ Dev. Growth Diff.
Citation
Fukuda, K., and Kikuchi, Y. (2005) Endoderm development in vertebrates: fate mapping, induction and regional specification. Development, growth & differentiation. 47(6):343-355.
Abstract
The formation of the vertebrate body plan begins with the differentiation of cells into three germ layers: ectoderm, mesoderm and endoderm. Cells in the endoderm give rise to the epithelial lining of the digestive tract, associated glands and respiratory system. One of the fundamental problems in developmental biology is to elucidate how these three primary germ layers are established from the homologous population of cells in the early blastomere. To address this question, ectoderm and mesoderm development have been extensively analyzed, but study of endoderm development has only begun relatively recently. In this review, we focus on the 'where', 'when' and 'how' of endoderm development in four vertebrate model organisms: the zebrafish, Xenopus, chick and mouse. We discuss the classical fate mapping of the endoderm and the more recent progress in characterizing its induction, segregation and regional specification.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping