|ZFIN ID: ZDB-PUB-050518-10|
Developmental Expression of NPY/PYY Receptors zYb and zYc in Zebrafish
Mathieu, M., Trombino, S., Argenton, F., Larhammar, D., and Vallarino, M.
|Source:||Annals of the New York Academy of Sciences 1040: 399-401 (Journal)|
|Registered Authors:||Argenton, Francesco, Larhammar, Dan|
|Keywords:||receptors; neuropeptides; ontogeny; zebrafish; whole-mount in situ hybridization|
|PubMed:||15891072 Full text @ Ann N Y Acad Sci|
Mathieu, M., Trombino, S., Argenton, F., Larhammar, D., and Vallarino, M. (2005) Developmental Expression of NPY/PYY Receptors zYb and zYc in Zebrafish. Annals of the New York Academy of Sciences. 1040:399-401.
ABSTRACTThis study describes the developmental expression of zYb and zYc receptors in zebrafish. RT-PCR demonstrated that both mRNAs are present from 24-hour postfertilization (hpf) and that their expression increased during larval development. Whole-mount in situ hybridization showed zYb mRNA expression in the epithalamus (24 hpf), telencephalon, hypothalamus, rhombencephalon (24-96 hpf), mesencephalon (48-96 hpf), hatching gland, and otic vesicle (48-64 hpf). zYc mRNA is expressed in the epithalamus (24 and 96 hpf), telencephalon (48-96 hpf), spinal cord, notochord (64 hpf), and hatching gland (96 hpf). These results show that zYb and zYc receptors are expressed during ontogeny, suggesting a role for neuropeptide Y (NPY) and/or peptide YY (PYY) in organogenesis.