PUBLICATION
Genetics moving to neuronal networks
- Authors
- Kullander, K.
- ID
- ZDB-PUB-050510-4
- Date
- 2005
- Source
- Trends in neurosciences 28(5): 239-247 (Review)
- Registered Authors
- Keywords
- none
- MeSH Terms
-
- Animals
- Humans
- Models, Neurological*
- Nerve Net/physiology*
- Motor Activity/genetics*
- Models, Genetic*
- PubMed
- 15866198 Full text @ Trends Neurosci.
Citation
Kullander, K. (2005) Genetics moving to neuronal networks. Trends in neurosciences. 28(5):239-247.
Abstract
Neuronal circuits are essential components of the nervous system and determine various body functions. To understand how neuronal circuits operate it is necessary to identify the participating neuronal subpopulations and to dissect the function of the neurons at the molecular level. The locomotor central pattern generator that coordinates body movements is well suited for elucidating the assembly and identity of the participating neurons. Remarkable advances in the field of genetics are making studies in neuroscience more efficient and precise so that now, using nematode worms, fruit flies, zebrafish and mice as model organisms, a genetic approach can be used to identify molecules and neurons crucial for locomotor network functionality.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping