PUBLICATION
beta-Naphthoflavone Caused Up-Regulation of AhR Regulated GFP in Transgenic Zebrafish
- Authors
- Seok, S.H., Park,, D., Park, J.H., Cho, S.A., Baek, M.W., Lee, H.Y., Kim, D.J., Jin, B., Ryu, D.Y., and Park, J.H.
- ID
- ZDB-PUB-041103-2
- Date
- 2004
- Source
- Experimental animals 53(5): 479-483 (Journal)
- Registered Authors
- Park, Jae-Hak
- Keywords
- aryl hydrocarbon receptor, green fluorescent protein, zebrafish
- MeSH Terms
- none
- PubMed
- none Full text @ Exp. Anim.
Citation
Seok, S.H., Park,, D., Park, J.H., Cho, S.A., Baek, M.W., Lee, H.Y., Kim, D.J., Jin, B., Ryu, D.Y., and Park, J.H. (2004) beta-Naphthoflavone Caused Up-Regulation of AhR Regulated GFP in Transgenic Zebrafish. Experimental animals. 53(5):479-483.
Abstract
A transgenic zebrafish strain was generated expressing the aryl hydrocarbon receptor (AhR)-regulated green fluorescent protein (GFP) reporter gene. Following exposure to beta-naphthoflavone (betaNF), the transgenic fish exhibited up-regulation of GFP in the face and vertebrae compared to vehicle controls. betaNF-exposed fish exhibited gross dysmorphogenesis in vertebral development by 5 days after fertilization.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping