PUBLICATION

Muscle differentiation: a gene for slow muscle?

Authors
Hughes, S.M.
ID
ZDB-PUB-040319-2
Date
2004
Source
Current biology : CB   14(4): 156-157 (Journal)
Registered Authors
Hughes, Simon M.
Keywords
none
MeSH Terms
  • Animals
  • Cell Differentiation
  • DNA-Binding Proteins
  • Gene Expression Regulation
  • Hedgehog Proteins
  • Muscle Development*
  • Muscle Fibers, Slow-Twitch/metabolism
  • Muscle Fibers, Slow-Twitch/physiology*
  • Muscle, Skeletal/embryology*
  • Myoblasts, Skeletal/cytology*
  • Nuclear Proteins
  • Repressor Proteins/genetics
  • Repressor Proteins/metabolism*
  • Trans-Activators/metabolism
  • Transcription Factors/genetics
  • Transcription Factors/metabolism*
  • Zebrafish
  • Zebrafish Proteins
PubMed
15027468 Full text @ Curr. Biol.
Abstract
Skeletal muscle comes in two fundamental flavours, slow and fast, which determine physiological performance. Zebrafish screens have provided a handle on the molecular mechanism driving slow muscle formation. The transcriptional repressor Blimp1 has now been shown to be required in embryonic slow muscle precursor cells.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes