PUBLICATION

Primordial germ-cell development: the zebrafish perspective

Authors
Raz, E.
ID
ZDB-PUB-030908-10
Date
2003
Source
Nature reviews. Genetics   4(9): 690-700 (Review)
Registered Authors
Raz, Erez
Keywords
none
MeSH Terms
  • Animals
  • Caenorhabditis elegans/cytology
  • Caenorhabditis elegans/embryology
  • Caenorhabditis elegans/genetics
  • Cell Differentiation
  • Cell Movement
  • Chemokine CXCL12
  • Chemokines, CXC/genetics
  • Drosophila melanogaster/cytology
  • Drosophila melanogaster/embryology
  • Drosophila melanogaster/genetics
  • Female
  • Gene Expression Regulation, Developmental
  • Germ Cells/cytology*
  • Humans
  • Male
  • Mice
  • Receptors, CXCR4/genetics
  • Species Specificity
  • Zebrafish/embryology*
  • Zebrafish/genetics
PubMed
12951570 Full text @ Nat. Rev. Genet.
Abstract
Primordial germ cells follow a characteristic developmental path that is manifested in the specialized regulation of basic cell functions and behaviour. Recent studies in zebrafish have greatly enhanced our understanding of the mode of specification of primordial germ cells, cell-fate maintenance and the migration of these cells towards their target, the gonad, where they differentiate into gametes.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping