PUBLICATION
Primordial germ-cell development: the zebrafish perspective
- Authors
- Raz, E.
- ID
- ZDB-PUB-030908-10
- Date
- 2003
- Source
- Nature reviews. Genetics 4(9): 690-700 (Review)
- Registered Authors
- Raz, Erez
- Keywords
- none
- MeSH Terms
-
- Cell Movement
- Species Specificity
- Zebrafish/embryology*
- Zebrafish/genetics
- Gene Expression Regulation, Developmental
- Drosophila melanogaster/cytology
- Drosophila melanogaster/embryology
- Drosophila melanogaster/genetics
- Germ Cells/cytology*
- Chemokine CXCL12
- Female
- Mice
- Animals
- Receptors, CXCR4/genetics
- Cell Differentiation
- Humans
- Chemokines, CXC/genetics
- Male
- Caenorhabditis elegans/cytology
- Caenorhabditis elegans/embryology
- Caenorhabditis elegans/genetics
- PubMed
- 12951570 Full text @ Nat. Rev. Genet.
Citation
Raz, E. (2003) Primordial germ-cell development: the zebrafish perspective. Nature reviews. Genetics. 4(9):690-700.
Abstract
Primordial germ cells follow a characteristic developmental path that is manifested in the specialized regulation of basic cell functions and behaviour. Recent studies in zebrafish have greatly enhanced our understanding of the mode of specification of primordial germ cells, cell-fate maintenance and the migration of these cells towards their target, the gonad, where they differentiate into gametes.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping