PUBLICATION

Understanding cardiovascular physiology in zebrafish and Xenopus larvae: the use of microtechniques

Authors
Schwerte, T. and Fritsche, R.
ID
ZDB-PUB-030602-4
Date
2003
Source
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology   135(1): 131-145 (Review)
Registered Authors
Schwerte, Thorsten
Keywords
none
MeSH Terms
  • Animals
  • Biosensing Techniques
  • Blood Cell Count/methods
  • Blood Vessels/anatomy & histology
  • Blood Vessels/physiology
  • Cardiovascular Physiological Phenomena*
  • Heart/anatomy & histology
  • Heart/physiology
  • Larva
  • Miniaturization
  • Monitoring, Physiologic/methods*
  • Monitoring, Physiologic/trends
  • Xenopus/anatomy & histology
  • Xenopus/physiology*
  • Zebrafish/anatomy & histology
  • Zebrafish/physiology*
PubMed
12727550 Full text @ Comp. Biochem. Physiol. A Mol. Integr. Physiol.
Abstract
Zebrafish and Xenopus, genetically accessible vertebrates with an externally developing, optically clear embryo, are ideally suited for in vivo functional dissection of the embryonic development of the circulatory system. Physiological characterizations of the cardiovascular system are still imperative for a more complete understanding of the connections between genetic/epigenetic factors and cardiovascular development. Here, we review experimental tools and methods that have been developed to measure numerous cardiovascular parameters in these millimetre-sized animals.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping